A tothpaste should be changed every couple of months or to be more specific, each time a toothpaste tube is finished, change to another one to give time for the mouth flora not to relax from one specific chemical product.
Your teeth wont be harmed if you change to another toothpaste.
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It is recommended that all individuals see a Family Doctor for a full medical examination annually. Adults should get their blood pressure checked (US Preventive Task Force), a flu vaccine (CDC) and more each year.