It is difficult to fortell, when a seropositive patient (if proven HIV positive) will developp the symptoms (remicade (anti-tnf) can give give flu like symptoms and adenopathy can be related to the underlying auto-immune disease for which you are taking MTX and remicade.
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It is recommended that all individuals see a Family Doctor for a full medical examination annually. Adults should get their blood pressure checked (US Preventive Task Force), a flu vaccine (CDC) and more each year.