The following side effects are common (occurring in greater than 30%) for patients taking methotrexate:
• Low blood counts: white and red blood cells and platelets may temporarily decrease. This can put the patient at increased risk for infection, anemia and/or bleeding.
Nadir (lowest cell count): Meaning low point, nadir is the point in time between therapy cycles in which you experience low blood counts.
Onset: 7 days
Nadir: 10 days
Recovery: 21 days
Just make sure that, during this period, you avoid eating outside, eating raw (uncooked) foods or at least cleanse them very well (soak vegetables in Presept for 10 min then wash with fresh water), avoid undercooked meat/poultry, avoid sick contacts (people with signs of illness), and injuries (as they may easily be complicated with a difficult-to-treat infection).