It is very simple. When a person is sad or when he is very anxious, he loses interest in many things like socializing or working or eating. Not eating enough or properly in addition to lack of adequate sleep causes sad people to lose weight.
First of all I would like to ask you if you are biologically a female and you feel like you are really a male, that's to say, you are a Trans sexual. If that is the case you need to live and practice the male role in the community for at least 3 years before your psychiatrist decides to take decisions like giving male hormones.
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It is recommended that all individuals see a Family Doctor for a full medical examination annually. Adults should get their blood pressure checked (US Preventive Task Force), a flu vaccine (CDC) and more each year.